The Sinister System is the creation of High Majesty Sinister and is the basis of his Sinister Empire. It consists of replacing humanity with the Sinister Species, and also of replacing much of the other lifeforms with Sinister equivalents as well. The entirety of the Sinister System is networked back to the High Majesty via psionics.

The system also informs society castes and tradition. The lowest class is that of the Sinister Plebeians, which happily fill their role in society.